HomeMedicalAsk the Expert: Understanding Benzodiazepines: Risks, Safety, and Alternatives

Ask the Expert: Understanding Benzodiazepines: Risks, Safety, and Alternatives

Benzodiazepines—commonly known as “benzos”—are a class of psychoactive medications frequently prescribed to manage conditions such as anxiety, insomnia, seizures, and muscle spasms. Medications like alprazolam (Xanax), diazepam (Valium), and lorazepam (Ativan) work by enhancing the calming effects of a neurotransmitter called GABA. When used short-term and under close medical supervision, benzodiazepines can offer rapid relief from acute symptoms.

However, long-term use or misuse of these medications presents significant risks. Over time, the body can develop tolerance, leading to increased dosage needs, physical dependence, and even withdrawal symptoms when stopping use. In some cases, benzodiazepine misuse can impair memory, reduce cognitive function, and increase the risk of accidental overdose—especially when combined with alcohol or other substances.

If you or someone you love is currently prescribed benzodiazepines or considering them for symptom relief, it’s essential to fully understand the associated risks and explore safer, evidence-based alternatives. For many people, non-addictive approaches—such as various types of therapy, including cognitive behavioral therapy for anxiety—can offer long-term healing without the downsides of prolonged medication use. In some cases, safer pharmacological options like selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), or other non-habit-forming medications may be appropriate and effective in managing symptoms with a lower risk of dependence.

At Crossroads Counseling Services, we understand that mental health treatment isn’t one-size-fits-all. Whether you’re seeking medications for anxiety, depression or insomnia, looking for support to taper off benzodiazepines safely, or searching for effective, sustainable care options like CBT exercises for anxiety or behavioral  strategies to manage ADHD, our compassionate team is here to help you take the next step forward—safely, supported, and without judgment.

What Are Benzodiazepines?

Benzodiazepines work by targeting the central nervous system, specifically by enhancing the activity of gamma-aminobutyric acid (GABA)—a neurotransmitter that plays a key role in slowing down nerve signals and promoting a sense of calm. By amplifying GABA’s natural effects, these medications can quickly reduce symptoms of anxiety, muscle tension, and panic.

Some of the most commonly prescribed benzodiazepines include:

  • Alprazolam (Xanax) – often used for generalized anxiety and panic disorders
  • Diazepam (Valium) – prescribed for anxiety, muscle spasms, and sometimes alcohol withdrawal
  • Lorazepam (Ativan) – used for severe anxiety or before medical procedures
  • Clonazepam (Klonopin) – commonly prescribed for panic disorders and certain types of seizures

While benzodiazepines can be effective in the short term—especially during moments of acute distress—they are not intended for long-term use. With prolonged use, the brain can become dependent on the medication, leading to tolerance (needing higher doses for the same effect), physical dependence, and, in some cases, severe withdrawal symptoms when stopping the drug.

Because of these risks, most medical guidelines recommend using benzodiazepines sparingly and for limited periods for short term relief. Fortunately, there are safer, evidence-based long-term treatment options that address the underlying causes of anxiety and related conditions. Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are often first-line medications for anxiety and panic disorders. These medications work by modulating serotonin and/or norepinephrine activity in the brain and have a much lower risk of dependence compared to benzodiazepines.

In addition to medication, cognitive behavioral therapy (CBT) remains a gold standard for long-term recovery. Techniques such as cognitive restructuring help individuals challenge distorted thinking patterns and reduce anxiety over time. When paired with healthy lifestyle habits, mindfulness practices, and consistent support, these approaches can empower individuals to manage symptoms without relying on potentially habit-forming medications.

The Risks of Benzodiazepine Use

Although benzodiazepines can provide rapid relief for acute anxiety or panic, their long-term use is associated with a number of serious and sometimes irreversible health risks. Many individuals start taking these medications with the understanding that they are safe and effective, but over time, chronic use—especially without regular medical oversight—can lead to complications that outweigh any initial benefits.

Here are some of the most concerning outcomes linked to prolonged or inappropriate benzodiazepine use:

  1. Physical Dependence and Withdrawal
    The human brain quickly adapts to the presence of benzodiazepines. With regular use, the body builds tolerance, requiring higher doses to achieve the same effect. This can evolve into physical dependence, where the body relies on the drug to function normally. When the medication is reduced or discontinued—especially abruptly—individuals may experience intense withdrawal symptoms. These can include severe rebound anxiety, insomnia, muscle pain, tremors, irritability, and, in some cases, life-threatening seizures. Withdrawal from benzodiazepines should never be attempted without professional support due to these risks.
  2. Cognitive Impairment and Memory Loss
    Research has consistently shown that long-term benzodiazepine use can impair cognitive functions, particularly memory, attention, and problem-solving abilities. Older adults may be especially vulnerable to these effects, but younger adults are not immune. Memory lapses, difficulty concentrating, and slowed processing speed are commonly reported, and in some cases, cognitive decline may persist even after discontinuing the medication. These side effects can interfere with daily functioning, employment, and overall quality of life.
  3. Increased Risk of Falls and Injury in Older Adults
    In aging populations, the use of benzodiazepines has been strongly associated with an increased risk of falls and fractures. Because these medications sedate the central nervous system and impair balance, coordination, and reaction time, older adults who take them are significantly more likely to experience injuries that can lead to hospitalization or long-term disability.
  4. Dangerous Interactions with Other Substances
    One of the most serious dangers of benzodiazepines is their potential for interaction with other central nervous system depressants, such as alcohol and opioids. These combinations can suppress breathing and heart rate to dangerously low levels, increasing the risk of overdose and death. In recent years, a significant number of fatal overdoses in the United States have involved both opioids and benzodiazepines—a deadly pairing that has led the FDA to issue warnings against co-prescribing these drugs.
  5. Long-Term Use Despite Short-Term Guidelines
    Perhaps most concerning is the gap between clinical guidelines and real-world prescribing practices. A recent study found that nearly 50% of benzodiazepine prescriptions in the United States are for long-term use—despite clear medical guidance that these drugs should be limited to short durations, typically no more than two to four weeks (Billioti de Gage et al.). This mismatch between recommendations and reality highlights the importance of educating patients and providers alike about the potential risks and encouraging safer, evidence-based alternatives.

Given these risks, it’s crucial for individuals taking benzodiazepines—or considering them—to have honest, informed conversations with their healthcare providers. Understanding the potential long-term effects is the first step toward making safer decisions about your mental health. Fortunately, there are effective, non-addictive alternatives that can help regulate mood, reduce anxiety symptoms, and improve emotional stability without compromising cognitive health or overall safety.

Therapy as a Safer, Evidence-Based Alternative

For many individuals seeking relief from anxiety, panic attacks, or insomnia, benzodiazepines may seem like a quick fix—but they are not the only, nor the safest, long-term solution. One of the most effective and sustainable alternatives is Cognitive Behavioral Therapy (CBT)—a research-backed, skills-based approach that has been widely regarded as a gold standard for treating the very same conditions benzodiazepines are often prescribed to manage.

CBT works by helping individuals identify and reframe unhelpful thought patterns that contribute to emotional distress and problematic behaviors. Through structured sessions with a trained therapist, patients learn how to challenge cognitive distortions, manage physiological symptoms of anxiety, and develop healthier coping mechanisms. In contrast to medication, which only dampens symptoms temporarily, CBT empowers individuals to make lasting changes that reduce the intensity and frequency of symptoms over time.

One of the most powerful aspects of CBT is its adaptability. It has been shown to be especially effective in treating:

  • Generalized Anxiety Disorder and Panic Disorder
  • Social Anxiety
  • Chronic Insomnia
  • Obsessive-Compulsive Disorder (OCD)
  • Post-Traumatic Stress Disorder (PTSD)

In fact, cognitive behavioral therapy for anxiety has become one of the most widely recommended treatments by both the American Psychological Association (APA) and the National Institute for Health and Care Excellence (NICE) due to its high efficacy and safety profile.

For those navigating attention-related challenges, CBT exercises for ADHD can also be incredibly beneficial. Unlike stimulant medications that target attention directly, CBT for ADHD focuses on developing concrete strategies for time management, task initiation, emotional regulation, and behavioral consistency. These tools help individuals regain control over their routines and build resilience in the face of everyday challenges.

If you’re currently exploring safer, drug-free options, simply searching for “cognitive behavioral therapy near me” can connect you with licensed professionals trained to help manage symptoms through personalized, evidence-based care. Some therapists also offer teletherapy sessions, making high-quality mental health support more accessible than ever.

And at the heart of CBT is cognitive restructuring—the process of identifying irrational beliefs and replacing them with balanced, realistic alternatives. This technique is especially powerful for those whose anxiety or panic is rooted in catastrophic thinking, past trauma, or deep-seated fears. Over time, cognitive restructuring not only reduces emotional suffering but also improves decision-making, confidence, and overall quality of life.

At Crossroads, we specialize in helping individuals find long-term healing through holistic, compassionate care. Whether you’re looking to taper off benzodiazepines safely, explore therapy as a primary treatment, or build resilience through personalized mental health support, our expert team is here to walk alongside you every step of the way.

Safer Medication Alternatives to Benzodiazepines

While therapy – especially CBT – remains a cornerstone for treating anxiety, insomnia, and related mental health conditions, some individuals may require more pharmacological support. Fortunately, not all of the medications in the market to treat these ailments carry the same risks of dependency and cognitive decline that benzodiazepines do.

A number of safer, evidence-based alternatives exist that can help manage symptoms without creating the same potential for long-term harm.

SSRIs and SNRIs: First-Line Treatments for Anxiety and Panic

Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are often considered a first line medication when it comes to anxiety disorders. Medications like Zoloft (sertraline), Lexapro (escitalopram), and Effexor (venlafaxine) do not create a rapid sedative effect. Instead, they work over time by balancing neurotransmitters that influence mood and stress response.

Though they may take several weeks to reach their full therapeutic effect, SSRIs and SNRIs have been extensively studied and shown to reduce the frequency and severity of panic attacks, generalized anxiety symptoms, and depressive episodes. They also have a significantly lower risk of addiction or withdrawal complications when discontinued under medical supervision.

Targeting Physical Symptoms with Antihistamines and Beta Blockers

If you are dealing with situational anxiety, like one might before a medical procedure or public speaking event, a short term use of a medication like hydroxyzine or propranolol may offer you targeted relief.

Beta blockers work to reduce the physical symptoms of anxiety like a racing heart, trembling, or nausea, without the risks of addiction. Meanwhile, hydroxyzine has sedative and anti-anxiety properties that help calm the nervous system without the risk of physical dependence. Although not typically used for long-term anxiety management, these medications can be valuable tools for specific situations or in individuals who cannot tolerate first-line treatments like SSRIs or SNRIs.

Buspirone: A Non-Sedating Anti-Anxiety Medication

Buspirone, another medication belonging to a class of drugs called anxiolytics, is often used as an alternative to benzodiazepines, particularly for those with generalized anxiety disorder. Unlike benzos, buspirone does not sedate the central nervous system or produce euphoric effects. It also carries no risk of physical dependence.

It may not be as fast acting as benzodiazepine, but buspirone is a well-tolerated option that helps to regulate anxiety over time – often leaving out the cognitive fog or withdrawal symptoms that accompany long term benzodiazepine use.

A Personalized Approach to Treatment

Mental health treatment should never be a one-size-fits-all experience. Everyone’s journey is different—shaped by personal history, biology, environment, and unique challenges. For some, short-term use of benzodiazepines may offer needed relief during a crisis or acute period of distress. But for many others, the long-term use of these medications can lead to a cycle of dependence and diminished quality of life.

This is where a personalized, evidence-based approach becomes essential. Types of eating disorder therapy such as Cognitive Behavioral Therapy (CBT), mindfulness-based stress reduction, and trauma-informed modalities can help individuals address the root causes of anxiety, panic, and insomnia—without relying on potentially habit-forming medications. These therapies don’t just mask symptoms; they provide actionable tools and strategies for sustainable healing.

Whether you’re new to therapy or revisiting it as a supplement to your current treatment plan, working with a licensed mental health professional can be a transformative step. A trained clinician can help determine the most effective path forward, whether that includes exploring cognitive restructuring, building emotional regulation skills through CBT exercises for ADHD, or seeking cognitive behavioral therapy for anxiety to replace reliance on benzodiazepines.

If you or someone you care about is struggling with benzodiazepine use or considering tapering off, it’s important to seek support. Discontinuing these medications should always be done under the guidance of a healthcare provider, ideally with integrated therapeutic care. Attempting to quit “cold turkey” can be not only ineffective but dangerous, especially if withdrawal symptoms are severe. Therapeutic support during this process can ease the transition and provide alternative strategies to manage underlying symptoms.

Final Thoughts

Understanding the risks associated with benzodiazepines is not about fear—it’s about empowerment. These medications can be effective tools when used appropriately and for a limited time. But they are not a long-term solution to chronic mental health concerns. Left unchecked, prolonged use can lead to significant cognitive, emotional, and physical consequences.

The good news is that healing is possible—and often, it starts with the decision to explore safer, more sustainable alternatives. Evidence-based therapies like CBT can help rewire how we think, feel, and respond to stress, offering lasting relief that doesn’t come with the baggage of dependency. Whether you’re curious about cognitive behavioral therapy near me, interested in non-medication options for anxiety, or navigating the challenges of benzo tapering, support is available—and you don’t have to do it alone.

At Crossroads, we’re committed to helping individuals break free from the grip of medication dependency and reclaim their mental well-being with dignity, care, and confidence. Reach out today to explore how we can help you chart a healthier path forward—because with the right tools and support, recovery isn’t just possible—it’s probable.

Works Cited

U.S. Food and Drug Administration. “FDA Requiring Boxed Warning for Updated Labeling to Improve Safe Use of Benzodiazepine Drug Class.” FDA, 2020, www.fda.gov/drugs/drug-safety-and-availability/fda-requiring-boxed-warning-updated-improve-safe-use-benzodiazepine-drug-class.

U.S. Food and Drug Administration. “FDA Drug Safety Communication: FDA Warns About Serious Risks and Death When Combining Opioid Pain or Cough Medicines with Benzodiazepines.” FDA, 2020, www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-warns-about-serious-risks-and-death-when-combining-opioid-pain-or.

Billioti de Gage, S., Moride, Y., Ducruet, T., & Béland, S. (2014). Benzodiazepine use and the risk of cognitive decline and dementia: A systematic review and meta-analysis. European Journal of Clinical Pharmacology, 70(9), 1051–1060. https://pubmed.ncbi.nlm.nih.gov/25517224

American Psychological Association. (2020). Cognitive Behavioral Therapy for anxiety disorders: A practitioner’s guide. APA Press.

Must Read
Related News